ISSN: 3107-4553

Implementing GDPR-Compliant Solutions for Genomics Data Analysis on HPC Cloud Infrastructure

Abstract

The rapid advancement of genomics data analysis on High-Performance Computing (HPC) cloud infrastructures presents unique challenges in ensuring compliance with the General Data Protection Regulation (GDPR). This study examines GDPR-compliant solutions for large-scale genomics data analysis, focusing on the strategies employed by the CINECA supercomputing center. Key research questions explore data security, compliance measures, efficient data processing, integration of diverse diagnostic data, and scalability across institutions. A quantitative research approach is employed, analyzing relationships between data security measures and compliance rates. Findings indicate that dynamic GDPR-compliant protocols, advanced encryption, optimized data processing, standardized integration processes, and adaptable frameworks significantly enhance security, efficiency, and compliance. The study contributes to the field by bridging gaps in scalable and secure genomics data processing, offering insights into sustainable GDPR-compliant implementations.

References

  1. Voigt, P., & von dem Bussche, A. (2017). The EU General Data Protection Regulation (GDPR): A Practical Guide. Springer
  2. Kaye, J. (2018). "The tension between data sharing and the protection of privacy in genomics research." Annual Review of Genomics and Human Genetics, 19, 371-392
  3. Erlich, Y., & Narayanan, A. (2014). "Routes for breaching and protecting genetic privacy." Nature Reviews Genetics, 15(6), 409-421
  4. Shabani, M., & Borry, P. (2018). "Rules for processing genomic data under the GDPR: A comparison of legal approaches." Journal of Medical Ethics, 44(8), 480-483
  5. Dyke, S. O., Dove, E. S., Knoppers, B. M., et al. (2018). "Sharing health-related data: A privacy test?" EMBO Molecular Medicine, 10(2), e8490
  6. Thorogood, A., Cook-Deegan, R., Knoppers, B. M., et al. (2018). "Public variant databases: Predicting privacy impacts and mitigating risks." Human Genetics, 137(7), 569-578
  7. Zook, M., Barocas, S., boyd, d., et al. (2017). "Ten simple rules for responsible big data research." PLoS Computational Biology, 13(3), e1005399
  8. Grossmann, C., Powers, B., McGinnis, J. M., & Daniels, J. P. (2011). Digital Infrastructure for the Learning Health System: The Foundation for Continuous Improvement in Health and Health Care. National Academies Press. European Data Protection Board (EDPB). (2019). "Guidelines on the processing of personal data under GDPR." Available at: https://edpb.europa.eu
  9. Langarizadeh, M., Moghbeli, F., & Aliabadi, A. (2018). "Application of ethics for providing a secure environment in telemedicine." Acta Informatica Medica, 26(2), 147-151
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How to Cite

Gnanzou, D., (2025/3/6). Implementing GDPR-Compliant Solutions for Genomics Data Analysis on HPC Cloud Infrastructure. JANOLI International Journal of Big Data , Volume ALIHWmliJRGzmKonHyii, Issue 1.